London, Feb 6: Small but powerful nanoparticles can now be used to grow stem cells safely in the lab, which could lead to cheaper transplant treatments and potentially help in generating whole human organs sans the need for donors, a study said.
The study, published in the journal Applied Materials and Interfaces, has found a new method for growing human embryonic stem cells, that doesn’t rely on supporting human or animal cells.
Traditionally, these stem cells are cultivated with the help of proteins from animals, which rules out their use in the treatment of humans.
Growing stem cells on other human cells also risks contamination with pathogens that could transmit diseases to patients.
The scientists of University of Surrey (Britain) in collaboration with professor Peter Donovan of University of California have developed a scaffold of carbon nanotubes upon which human stem cells could be grown into a variety of tissues.
These new building blocks mimic the surface of the body’s natural support cells and act as scaffolding for stem cells to grow on.
Cells that have previously relied on external living cells could now be grown safely in the lab, paving the way for revolutionary steps in replacing tissue after injury or disease, reports Science Daily.
Alan Dalton, senior lecturer at Surrey University’s physics department, said: “While carbon nanotubes have been used in the field of biomedicine for some time, their use in human stem cell research has not previously been explored successfully.”
“Synthetic stem cell scaffolding has the potential to change the lives of thousands of people, suffering from diseases such as Parkinson’s, diabetes and heart disease, as well as vision and hearing loss,” he said.
“It could lead to cheaper transplant treatments and could potentially one day allow us to produce whole human organs without the need for donors,” Dalton added.